JIAB-2026-ZVA4
Bayesian Inference in Clinical Trials: A Practical Guide
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Abstract
We present a practitioner-oriented introduction to Bayesian methods for adaptive clinical trial design. Using three motivating case studies from oncology, we demonstrate how posterior predictive distributions enable principled early stopping and sample-size re-estimation without inflating type-I error.
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1 messageA Author Cover letter
I am pleased to submit this manuscript for consideration. The work addresses a long-standing gap between Bayesian theory and trial practice.
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